Any new or unusual symptom after dosing. Because this compound has little or no human safety data, there is no established list of 'expected' effects to reassure you against — treat anything abnormal as a signal.
Stop at the first clearly abnormal reaction and reassess. Keep the vial and lot number in case you need to describe what you actually took.
Any severe or fast-worsening symptom — difficulty breathing, chest pain, fainting, severe pain — is a 911 call regardless of the compound.
Allergic reaction: hives, swelling of the lips, tongue or throat, wheezing or dizziness can escalate to anaphylaxis within minutes — call 911 immediately. Site infection: spreading redness, heat, swelling, pus or fever is not wait-and-see; an abscess or cellulitis can need drainage or IV antibiotics. Unverified product: grey-market vials are frequently mislabelled or contaminated, so a reaction may be to endotoxin or the wrong contents, not the named compound.
The only human cathelicidin. It is cationic and amphipathic, so it inserts into and disrupts negatively charged bacterial membranes directly — a physical mechanism to which resistance develops poorly. It also acts as a signalling molecule via FPR2, recruiting immune cells and modulating wound repair. Vitamin D upregulates its expression, which is a substantial part of the vitamin D-immunity story.
Large preclinical and mechanistic literature. Early human work in venous leg ulcers exists. Systemic therapeutic use is constrained by a real problem: the same membrane-disrupting property that kills bacteria is cytotoxic to host cells at higher concentrations.
Not FDA-approved.
Cytotoxicity and haemolysis at elevated concentrations are intrinsic to the mechanism, not an incidental impurity effect. Also implicated in the pathology of rosacea and in autoimmune processes in psoriasis and lupus — more of this peptide is not straightforwardly better.
No established systemic human dose; human work is limited to early topical wound studies.
Reported from clinical trials or FDA labelling as a matter of record. It is not a recommendation, and for unapproved compounds no dose has been shown safe or effective in humans.
Above is what was administered in trials or on FDA labels, reported as fact. We do not convert it into a personal protocol, calculate a dose for your body weight, or tell you what to inject or how to reconstitute it — that decision belongs with a licensed physician. See our editorial policy.
Regulatory status changes. This page reflects our reading of public sources as of July 2026 and should be independently verified before it is relied upon.