Puffiness and fluid retention in the hands and feet, joint aches, wrist tingling (carpal tunnel), and blood sugar creeping up over weeks — most pronounced with MK-677 and somatropin.
These accumulate rather than strike suddenly — reassess and stop rather than pushing the dose up. Check glucose if you can.
A severe persistent headache with vision changes (possible raised intracranial pressure), or symptoms of very high blood sugar — extreme thirst, confusion, vomiting — warrant urgent care.
Allergic reaction: hives, swelling of the lips, tongue or throat, wheezing or dizziness can escalate to anaphylaxis within minutes — call 911 immediately. Site infection: spreading redness, heat, swelling, pus or fever is not wait-and-see; an abscess or cellulitis can need drainage or IV antibiotics. Unverified product: grey-market vials are frequently mislabelled or contaminated, so a reaction may be to endotoxin or the wrong contents, not the named compound.
A hexapeptide ghrelin-receptor agonist that stimulates pituitary GH release. Less selective than ipamorelin — it produces measurable increases in cortisol and prolactin alongside GH.
Approved in Japan as a diagnostic agent for assessing growth hormone secretory reserve, which is its one well-established human use. Evidence for therapeutic use is absent.
Not FDA-approved. Approved in Japan as a diagnostic (Pralmorelin/GHRP Kaken). Prohibited in sport (WADA S2).
Cortisol and prolactin elevation distinguish it from selective agents. Long-term human safety not characterised.
Diagnostic use (Japan): 100 mcg IV as a GH-stimulation test. No therapeutic dose has been established.
Reported from clinical trials or FDA labelling as a matter of record. It is not a recommendation, and for unapproved compounds no dose has been shown safe or effective in humans.
Above is what was administered in trials or on FDA labels, reported as fact. We do not convert it into a personal protocol, calculate a dose for your body weight, or tell you what to inject or how to reconstitute it — that decision belongs with a licensed physician. See our editorial policy.
Regulatory status changes. This page reflects our reading of public sources as of July 2026 and should be independently verified before it is relied upon.