Any new or unusual symptom after dosing. Because this compound has little or no human safety data, there is no established list of 'expected' effects to reassure you against — treat anything abnormal as a signal.
Stop at the first clearly abnormal reaction and reassess. Keep the vial and lot number in case you need to describe what you actually took.
Any severe or fast-worsening symptom — difficulty breathing, chest pain, fainting, severe pain — is a 911 call regardless of the compound.
Allergic reaction: hives, swelling of the lips, tongue or throat, wheezing or dizziness can escalate to anaphylaxis within minutes — call 911 immediately. Site infection: spreading redness, heat, swelling, pus or fever is not wait-and-see; an abscess or cellulitis can need drainage or IV antibiotics. Unverified product: grey-market vials are frequently mislabelled or contaminated, so a reaction may be to endotoxin or the wrong contents, not the named compound.
A synthetic tetrapeptide derived from work on pineal extract (epithalamin) conducted in the Soviet Union and Russia. The claimed mechanism is induction of telomerase activity and consequent telomere maintenance. This mechanism is not independently validated, and the leap from a tetrapeptide to telomerase regulation is not mechanistically explained in the available literature.
The evidence base is the problem. Reports of lifespan extension and telomerase effects originate almost exclusively from a single research lineage, largely published outside mainstream peer review, and have not been independently replicated. Human data are sparse and methodologically weak. This is a peptide where marketing claims dramatically outrun the science.
Not FDA-approved. No approved product in any major jurisdiction.
No meaningful safety data. Note that a compound genuinely capable of inducing telomerase would warrant serious oncological scrutiny — telomerase reactivation is a hallmark of malignancy. The absence of that scrutiny reflects the weakness of the evidence, not the safety of the compound.
No credible human trial dose. Russian reports describe short parenteral courses that have not been independently validated.
Reported from clinical trials or FDA labelling as a matter of record. It is not a recommendation, and for unapproved compounds no dose has been shown safe or effective in humans.
Above is what was administered in trials or on FDA labels, reported as fact. We do not convert it into a personal protocol, calculate a dose for your body weight, or tell you what to inject or how to reconstitute it — that decision belongs with a licensed physician. See our editorial policy.
Regulatory status changes. This page reflects our reading of public sources as of July 2026 and should be independently verified before it is relied upon.